Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLYYSP-GACSLAAHIILNEINVDFDLERVNLKTHKTEKGADYYEINPKGYVPALEINPGLILTENVAILPFLAQHDPKQD-LIPPSG-LGRAKVLEWLGYLNSELHDAYAVFFGAPLTNDEKTKAYAEIDRLLKYIDNYLAESDYDYLVNDNFGPADAYLFVLTNWSNSIEHDLTPYKHIIALRNKVAERQSVQIAMRDEGLIS 1PMT Chain:A ((1-200)) MKLYYTPGS-CSLSPHIVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDNGDILTEGVAIVQYLADLKPDRNLIAPP-KALERYHQIEWLNFLASEVHKGYSPLFSSDTPESYLPVVKNKLKSKFVYINDVLS--KQKCVCGDHFTVADAYLFTLSQWAPHVALDLTDLSHLQDYLARIAQRPNVHSALVTEGL--

General information: TITO was launched using: RESULT: Template: 1PMT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 858 -34367 -40.05 -174.45 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : -40.05 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.566

(partial model without unconserved sides chains): PDB file : Tito_1PMT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PMT-query.scw PDB file : Tito_Scwrl_1PMT.pdb: