Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MARMAKVVELPSIAKIDKSKGKISAQLTQALREAVQSGDLQPGDPLPSSRELALTLGVARGTIIEAYDQLLAEGVFDSQPRTGTYVSHALVKTSAIQHSSKENKPNSISLNKSARSYAKVLDEFKPLPHVPFAVSVPIARTQPSDIWRKFGNKFRSRGAGVPSGYGEPQGVLSLRIAIADYVRRSRSVHCEPEQIVITPSIQQSLYICNQILFEAKDEVWVEDPAYRGTTAIFEHTVQNIRMVRVPVDEEGIQIETGIKL-S------KQASAAFVTPSHQYPLGMPMSLARRTALLAWAKQQNAWIIEDDYDSELRYNGQPFPSLQGMAP-DQAIYLGTFSKVLFPSLRLGYAVLPKELVAPFCGLRVLIDRHPPAADQHVLAAFIQEGYLERHIRRTRNVYAEVREYIIGLIEKYIPQELAWLQLGDQGMHMVLWLAQHINDIDVASSAVDAGIAIKAISPTFSKERRRSGLIVGLGDFEPELMQQAIKKLSKIIQQHAKSM 1X0M Chain:A ((56-427)) ------------------------------------------------------------------------------------------------------------------------------SDIISLAGGLPNPKTFPKEIIRDILVEIMEKYADKALQYGTTKGFTPLRETLMKWLGKRYGIS-QDNDIMITSGSQQALDLIGRVFLNPGDIVVVEAPTYLAALQAFNFYEP--QYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVYTVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDDPYGELRYSGNPEKKIKALDNEGRVIYLGTFSKILAPGFRIGWMVGDPGIIRKMEIAKQSTDLCTNVFGQVVAWRYVDGGYLEKHIPEIRKFYKPRRDAMLEALEEFMPEGVKWT-KPEGGMFIWVTLPDGIDSKKMLERAIKKGVAYVPGEAFYAHRDVKNTMRLNFTYVDEDKIMEGIKRLAETIKEELK--

General information: TITO was launched using: RESULT: Template: 1X0M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2069 -41705 -20.16 -114.57 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -20.16 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.475

(partial model without unconserved sides chains): PDB file : Tito_1X0M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1X0M-query.scw PDB file : Tito_Scwrl_1X0M.pdb: