Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTVAMSIMISTEEIQAKVKELGEQINSHYANSD-----KELVLIGLLRGSVIFMADLCRTITK---PHELDFMTVSSYGGGTTSSRDVKILKDLDGEIRGKDVLVVEDIIDSGNTLSKVVEMLQTREPNSIQLCTLVCKPSRREIDLEVKFLGFEVEDKFIVGYGLDYDQKYRHLPFIGEIGL 1P18 Chain:B ((8-179)) ---AEKILFTEEEIRTRIKEVAKRIADDYKGKGLRPYVNPLVLISVLRGSFMFTADLCRALCDFNVPVRMEFICVSSYGEGLTSSGQVRMLLDTRHSIEGHHVLIVEDIVDTALTLNYLYHMYFTRRPASLKTVVLLDKREGRRVPFSADYVVANIPNAFVIGYGLDYDDTYREL--------

General information: TITO was launched using: RESULT: Template: 1P18.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 790 -26266 -33.25 -160.16 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : -33.25 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.633

(partial model without unconserved sides chains): PDB file : Tito_1P18.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1P18-query.scw PDB file : Tito_Scwrl_1P18.pdb: