Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFHRQVEFLGGRYACKEAFSKAWGTGIGKVPFKMSRF 1FTH Chain:A ((3-79)) MIVGHGIDIEELASIESAVTRHEGFAKRVLTALEMERFTSLKGRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLE-

General information: TITO was launched using: RESULT: Template: 1FTH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 198 -24435 -123.41 -317.33 target 2D structure prediction score : 0.81 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -123.41 2D Compatibility (Sec. Struct. Predict.) : 0.81 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.573

(partial model without unconserved sides chains): PDB file : Tito_1FTH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FTH-query.scw PDB file : Tito_Scwrl_1FTH.pdb: