Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MILEIMMKVKNIQSETAMKQHSESVVSNQFEPTCHSEHSSVSDVCSSSAFGLATRSSRARMKRASGFTLIEVMVVIVILGVLAALIVPNVMGRSEKAKIDTTQITLKGVAGALDQYKLDNGHFPTMQEGGLDALINQPAT---AKNWMPGGYVKGGYPKDSWKNDIQYVVPGKDDHPFDLYSFGADGKEGGEGN--DADIYYQP 1T92 Chain:A ((2-109)) -------------------------------------------------------------------------------------------GNKEKADRQKVVSDLVALEGALDMYKLDNSRYPTTEQG-LQALVSAPSAEPHARNYPEGGYIRR-LPQDPWGSDYQLLSPG-QHGQVDIFSLGPDGVPESNDDIGNWTIGF--

General information: TITO was launched using: RESULT: Template: 1T92.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 400 7440 18.60 72.23 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 18.60 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_1T92.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1T92-query.scw PDB file : Tito_Scwrl_1T92.pdb: