Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDRRTDMRAVVQRVSKAAVSVDQQEIGK-------IGYGLLVLLGIHETDTQKDVDYLVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETAIPLYESFNEGIRSR--GITVATGQFGADMSVSLVNDGPVTIIIDSKNK 3KO4 Chain:B ((1-157)) ------MRVVIQRVKGAILSVR------ELEIISEIKNGLICFLGIHKNDTWEDALYIIRKCLNLRLWNNDNKTWDKNVKDLNYELLIVSQFTLFGNTKKGNKPDFHLAKEPNEALIFYNKIIDEFKKQYNDDKIKIGKFGNYMNIDVTNDGPVTIYIDT---

General information: TITO was launched using: RESULT: Template: 3KO4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 622 2488 4.00 17.90 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.80 3D Compatibility (PKB) : 4.00 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.574

(partial model without unconserved sides chains): PDB file : Tito_3KO4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3KO4-query.scw PDB file : Tito_Scwrl_3KO4.pdb: