Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRPTVLCFSGLDPSGGAGLQADIEAIGQSGAHAAIACTALTIQNSQQVFGSEATSKELLLAQANAVVGDLPIKCVKSGMLGTTDNIAALAEFLRAHPDYQYVLDPVLVANSGGSLGDQATLVKAFVELIL-LATLITPNTVELRALTGVT------DLDQATQKLFEMGAKAVLVKGGHEDTPDFIKNSLYIDGELAASSTCPRLE-GEYHGSGCSLASFIAGRLALGDSLKIAVQHAETWLFGVLKNAETPV-PNGQKIPKRF 1JXI Chain:B ((25-283)) -RINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAENTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNVVLDTVMLAKSGDPLLS-PSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLAMGCEAVLMKG----------DWLFTRE-GEQRF---RVNTKNTHGTGCTLSAALAALRPRHRSWGETVNEAKAWLSAALAQADTLEVGKGIGPVHH-

General information: TITO was launched using: RESULT: Template: 1JXI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1339 -88117 -65.81 -370.24 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain B : 0.77 3D Compatibility (PKB) : -65.81 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.536

(partial model without unconserved sides chains): PDB file : Tito_1JXI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JXI-query.scw PDB file : Tito_Scwrl_1JXI.pdb: