Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MITVSRKKRGSKKMKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPEKFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFYRDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVKKWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEIGIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMPEIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMNPYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEFVTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKSGRWFKTVSEKNGFDA 1BGG Chain:C ((2-442)) --------------TIFQFPQDFMWGTATAAYQIEGAYQEDGRGLSIWDT-FAHTPGKVFNGDNGNVACDSYHRYEEDIRLMKELGIRTYRFSVSWPRIFPNGDGEVNQEGLDYYHRVVDLLNDNGIEPFCTLYHWDLPQALQDAGGWGNRRTIQAFVQFAETMFREFHGKIQHWLTFNEPWCIAFLSNMLGVHAPGLTNLQTAIDVGHHLLVAHGLSVRRFRELGTSGQIGIAPNVSWAVPY-STSEEDKAACARTISLHSDWFLQPIYQGSYPQFLVDWFAEQGATVPIQDGDMDIIGE-PIDMIGINYY-----SMSVNRFNPEAGFLQSEEI-NMGLPVTDI----GWPVESRGLYEVL-HYLQKYGNIDIYITENGACINDE--VVN--GKVQDDRRISYMQQHLVQVHRTIHDGLHVKGYMAWSLLDNFEWAEGYNMRFGMIHVDF-RTQVRTPKESYYWYRNVVSNN----

General information: TITO was launched using: RESULT: Template: 1BGG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 2643 -199187 -75.36 -451.67 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain C : 0.79 3D Compatibility (PKB) : -75.36 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.412

(partial model without unconserved sides chains): PDB file : Tito_1BGG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1BGG-query.scw PDB file : Tito_Scwrl_1BGG.pdb: