Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTINYVLEQGG-KAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRG-EQLEEAIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHASNVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKADKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAG---DKLVLPIDNVCAPEFSNDVETQVIE-GDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTIGVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAAINDK 1V6S Chain:A ((2-390)) ---RTLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLA-GGASLVLLSHLGRPKGPD-P-KYSLAPVGEALRAHLPE-ARFAPFPPGSEEARREAEALRPGEVLLLENVRFE----PGEEKNDPELSARYARLGEAFVLDAFGSAHRAHASVVGVARL-LPAYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFTFLKALGGEVGRSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVETRVFPARAIPVPYMGLDIGPKTREAFARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAIAALEGAFTVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFLEKGTLPGLEVLEG-

General information: TITO was launched using: RESULT: Template: 1V6S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2325 42639 18.34 111.33 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : 18.34 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.677

(partial model without unconserved sides chains): PDB file : Tito_1V6S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1V6S-query.scw PDB file : Tito_Scwrl_1V6S.pdb: