Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKDLGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLVINHSSDQHQWFEESKKSKESPYRDYYIW--VDGVDGK----EPNNWTSIFGGSAWEYSHETGQYYLHVFAKEQPDLNWESEKLKEELF-NMIRWWLDKGIDGFRLDAISHVKK----------DEYSVKATENPFSPFQNVSGIEEHLTDLKH-----VFEEYDIMTVGEASGVTAEEGPQWVGKDGY-FDMIFEFDHIHIWQQEKEGQLDVLKLKLA---LSAWQTSLDGI--------GWNALYMENHDVPRAVSVFGDTRPDFWAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAE-GKTREEA---LDIIRETTRDNSRTPMQWTSEQ-YAGFS--THEPWLITNPNTKT-INVEQQEYEPESVLQFYKNMIRIRQTNKGL-IYGSYKEYLH-EHPQLYVYERYLEDEQYLIMVNLTESLADYELPKEADQSWTLLLSNSSSGEFEAKG-ILAPYEARLYKTNK 3AXH Chain:A ((11-586)) ---EPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQSSDPYT--LNGPRIHEFHQEMNQFIRNRVKDGREIMTVGAMQHASDETKRLYTSASRHELSELFNFSHTDV------GTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAALNFSSDATDFKIPND-DSSFKLEFGNYPKKEVDASSRTLKPWEGRIY----

General information: TITO was launched using: RESULT: Template: 3AXH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3104 88579 28.54 166.81 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.80 3D Compatibility (PKB) : 28.54 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.80 QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_3AXH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AXH-query.scw PDB file : Tito_Scwrl_3AXH.pdb: