Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVAQNTRGVQLIEHVSPQMLKAQLESIFSDIPPQAVKTGMLATTEIMEIIQPYLKK-LDCPYVLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIH-DPEDMQRAGRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQL--GHGSGPVNHTTFKD 1JXI Chain:B ((23-285)) -MQRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAENTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNVVLDTVMLAKSGDPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLAQGRALLA-MGCEAVLMKG--------DWLFTREGEQRF---RVNTKNTHGTGCTLSAALAALRPRHRSWGETVNEAKAWLSAALAQADTLEVGKGIGPVHHFH---

General information: TITO was launched using: RESULT: Template: 1JXI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1437 -78267 -54.47 -316.87 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain B : 0.82 3D Compatibility (PKB) : -54.47 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.476

(partial model without unconserved sides chains): PDB file : Tito_1JXI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JXI-query.scw PDB file : Tito_Scwrl_1JXI.pdb: