Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDKTARQKILDAAATLFYNDGITATGINTVTAKADVAKMSLYNNFSSKGELVDAYIAARHQEWLDLYQKRLE-KTKTAKEAILAVFDAYQDHAEFAYEKGFRGCGLLNAAAEFPA-NSSGRNAVRQHKEQVEAIVAEHLNRL----LKDSQRVSYIASQLSFLLEGSMARAGLEGSSRQLQLARQMAEDILDRECQHD 4L62 Chain:H ((1-187)) -SYDDTRQHLLDTGYRIMAVKGFSGVGLNEILQSAGVPKGSFYHYFKSKEQFGQALLEDYFRVYLADMDQRFSAPGLNARERLMSYWQKWLDNACP--PCDEQRCLVVKLSAEVADLSESMRITLRDGSDGIIERLVGCLGQGRDDGSLAPCDARHMASALYQLWLGASLLSKLHRSPGPLETAMQTTRS---------

General information: TITO was launched using: RESULT: Template: 4L62.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain H - contact count / total energy / energy per contact / energy per residue : 666 -24346 -36.56 -134.51 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain H : 0.72 3D Compatibility (PKB) : -36.56 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.572

(partial model without unconserved sides chains): PDB file : Tito_4L62.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4L62-query.scw PDB file : Tito_Scwrl_4L62.pdb: