Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MFISFEGTEGVGKTTLIR----KIHQHFEEQGKQVVLTREPGGTPLAEQIRSMLLAVNHDENMSHDTELLLIYAARAQHLQQVILPALESNKIVLSDRFTDASFAYQCSGRGLSQDKLQLLNQNFVSRM-PEVTFWLDAPIELGMNRARERGAL---DRFEQEKLSFFTKVREGYETLWKAEPERIKRLDATQSPDQVFEQALQYLA 3V9P Chain:A ((27-225)) -FITFEGID---KTTHLQWFCDRLQERLGPAGRHVVVTREPGGTRLGETLREILL----NQPMDLETEALLMFAGRREHLALVIEPALARGDWVVSDRFTDATFAYQGGGRGLPRDKLEALERWVQGGFQPDLTVLFDVPPQIASAR---RGAVRMP---ESESDAFFARTRAEYLRRAQEAPHRFVIVDSSEPIAQIRKQLEGVLA

General information: TITO was launched using: RESULT: Template: 3V9P.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 756 5058 6.69 27.34 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.81 3D Compatibility (PKB) : 6.69 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.534

(partial model without unconserved sides chains): PDB file : Tito_3V9P.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3V9P-query.scw PDB file : Tito_Scwrl_3V9P.pdb: