Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSMLV-----EAREASEEDLLVVHTRRYLNELKWSFAVA--TITEIPPVIFLP-----NFLVQRKVLRPLRTQTGGTIMAGKLAVERG--WAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMDDKRVYIMDVY--NRHIYP--GDRFAKQAIRRK-----------VELEWGTEDDEYLDKVERNIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDE----LVFRMVRGRRVPILMVTSGGY-QKRTARIIADSILNLFGLG-----LIGPESPSVSAQNSDTPLLPPAVP---------------------------------------------------- 4BZ7 Chain:C ((2-446)) --------------SVGIVYGDQYRQLCCS----SPKFGDRYALVMDLINAYKLIPELSRVPPLQWDSPSRMYEAVTAFHSTEYVDALKKLQMLHCEELTADDELLMDSFSLNYDCPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASGFCYLNDIVLAIHRLVSS----TRVLYVDLDLHHGDGVEEAFWYSPRVVTFSVHHASPGFFPGTGTWNMKLPIFLNGAGRGRFSAFNLPLEEGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNFYPSECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLWTRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPHETLDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR

General information: TITO was launched using: RESULT: Template: 4BZ7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1924 -67011 -34.83 -206.19 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain C : 0.66 3D Compatibility (PKB) : -34.83 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.387

(partial model without unconserved sides chains): PDB file : Tito_4BZ7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BZ7-query.scw PDB file : Tito_Scwrl_4BZ7.pdb: