Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WYVSYITRPEAEAALRKINQDGTFLVRDSSKKTTTNPYVLMVLYKDKVYNIQIRYQKESQVYLLGTGL-RGKEDFLSVSDIIDYF 1KA6 Chain:A ((6-87)) VYHGKISRETGEKLLLATGLDGSYLLRDSE--SVPGVYCLCVLYHGYIYTYRVSQT-ETGSWSAETAPGVHKRYFRKIKNLISAF

General information: TITO was launched using: RESULT: Template: 1KA6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 280 -43837 -156.56 -541.20 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : -156.56 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.654

(partial model without unconserved sides chains): PDB file : Tito_1KA6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KA6-query.scw PDB file : Tito_Scwrl_1KA6.pdb: