Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ----------CFYTVSRKEATEMLQKNPSLGNMILRPGSDSR-NYSITIRQEIDIPRIKHYKVMSV-GQNYTIELEKPVTLPNLFSVIDYF--------- 3GXW Chain:A ((2-102)) SHMHRVINHPYYFPFNGKQAEDYLRSKER-GDFVIRQSSRGDDHLAITWKLD---KDLFQHVDIQEMGKVLVVE---GQRYHDLDQIIVEYLQNKIRLLN

General information: TITO was launched using: RESULT: Template: 3GXW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 255 -9427 -36.97 -130.92 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : -36.97 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.576

(partial model without unconserved sides chains): PDB file : Tito_3GXW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3GXW-query.scw PDB file : Tito_Scwrl_3GXW.pdb: