Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGDVIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPFIRKAIKDQIASLSSNHPLVIVDIPLLYEG-HYDHYMDAVAVVYTTPETQLQRLMKRNQLTLEQAQQRISSQLPIEEKKQRADILFDNN-GTKEKLVGQIENWLFANRFL 4I1U Chain:B ((8-203)) -----------HMYAIGLTGGIGSGKTTVADLFAARGASLVDTDLIAHRITAPAGLAMPAIEQTFGPAFVAADGSLDRARMRALIFSDEDARRRLEAITHPLIRAETEREARD--AQGPYVIFVVPLLVESRNWKARCDRVLVVDCPVDTQIARVMQRNGFTREQVEAIIARQATREARLAAADDVIVNDAATPDALAVQVDALHQRYL--

General information: TITO was launched using: RESULT: Template: 4I1U.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 859 -72526 -84.43 -373.85 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain B : 0.78 3D Compatibility (PKB) : -84.43 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.78 QMean score : 0.633

(partial model without unconserved sides chains): PDB file : Tito_4I1U.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4I1U-query.scw PDB file : Tito_Scwrl_4I1U.pdb: