Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVAQIRIGQGMDVHAFEEGKFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH 3P0Z Chain:C ((24-177)) ----FRIGQGYDVHQLVPGRPLIIGGVTIPYERGLLGHSDADVLLHAITDALFGAAALGDIGRHF------FKGADSRALLRECASRVAQAGFAIRNVDSTIIAQAPKLAPHIDAMRANIAADLDLPLDRVNVKAKTNEKLGYLGRGEGIEAQAAALV--

General information: TITO was launched using: RESULT: Template: 3P0Z.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 840 -123472 -146.99 -834.27 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain C : 0.82 3D Compatibility (PKB) : -146.99 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.604

(partial model without unconserved sides chains): PDB file : Tito_3P0Z.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P0Z-query.scw PDB file : Tito_Scwrl_3P0Z.pdb: