Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVEWRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHVIHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVMEHFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGSVMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL 2O7S Chain:A ((2-251)) ----------KNPSLICAPVMADSIDKMVIETSKAHELGADLVEIRLDWLKDFNPL----EDLKTIIKKSP-LPTLFTYRPKWEGGQYEGDENERRDVLRLAME-LGADYIDVELQVASEFIKSID-GKKPGKFKVIVSSHNYQNTPSVEDLDGLVARIQQTGADIVKIATTAVDIADVARMFHITSK----AQVPTIGLVMGERGLMSRILCSKFGGYLTFGTLDSSKVSAPGQPTIKDLLDLYNFR----

General information: TITO was launched using: RESULT: Template: 2O7S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1248 -125603 -100.64 -553.31 target 2D structure prediction score : 0.57 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -100.64 2D Compatibility (Sec. Struct. Predict.) : 0.57 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.513

(partial model without unconserved sides chains): PDB file : Tito_2O7S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2O7S-query.scw PDB file : Tito_Scwrl_2O7S.pdb: