Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIKLNPLNAIDFYKADHRRQYPAGTEYVYANFTPRSSRLAKMLPDFDDKVVFFGLQGFIKHFLIDTWNEGFFKQPKDKVVAAYKRRMDSSLGEG---AVPVDHIEALHDLGYLPLRIKALPEGSRVNMRVPVLTVINTDPRFFWLTNYIETVLSAELWKSCTTATIAYEYKRLLTQYAVKTGAPLDFVPVQGHDFSSRGMSGIYDAAQSGVGHLTSFIGTDSVASIDYAEEYYNAT-GVIGVSVPATEHSVMCMGTEDNELETFKRLICELYPSGVVSIVSDTWDFWRVITEFTV-ALKPEILARQPNALGLAKLVFRPDSGDPVKIICGDPDAKVGSPAYKGAVECLWEVFGGTTTDQGYKVLNECVGLIYGDSITLDRAQRILEGLETKGFASNNLVFGIGSFTYNYLTRDTFGFAVKATWGQVNGVGRELFKDPITDSGVKKSAKGLLRIEE-SENGFTLFDQQTAE--QEQGGALKTVFENGKLQYECTLDQIRERLSIA 4LVF Chain:A ((8-483)) ---EFNILLATDSYKVTHYKQYPPNTSKVYSYFECREK--------KYEETVFYGLQYILNKYLK-GKV---VT---KEKIQEAKDVYKEHFQDDVFNEKGW-NYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILV-QSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVT-QFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRS----TQAPLIIRPDSGNPLDTVLK-------------VLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPN-KRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLN

General information: TITO was launched using: RESULT: Template: 4LVF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2501 22802 9.12 49.79 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 9.12 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.471

(partial model without unconserved sides chains): PDB file : Tito_4LVF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LVF-query.scw PDB file : Tito_Scwrl_4LVF.pdb: