Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIDSEGFRPNVGIILANDDGQVLWAKRIG-HNAWQFPQGGIQFGETPEQALFRELREEIGLLPEHVQIIAQTKGWLRYRLPHRY-----IRSDSDPVCIGQKQKWFLLKLTAPAKNIQL--NLADPPEFDEWQWVSYWYPLGQVVNFKRDVYRKAMVELCTQLPVQQLP 1JKN Chain:A ((11-165)) ----EGYRRNVGICLMNNDKKIFAASRLDIPDAWQMPQGGIDEGEDPRNAAIRELREETGVT--SAEVIAEVPYWLTYDFPPKVREKLNIQWGSD--WKGQAQKWFLFKFTGQDQEINLLGDGSEKPEFGEWSWVTPEQLIDLTVEFKKPVYKEVLSVFAPHL------

General information: TITO was launched using: RESULT: Template: 1JKN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 715 1636 2.29 11.13 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : 2.29 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.416

(partial model without unconserved sides chains): PDB file : Tito_1JKN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1JKN-query.scw PDB file : Tito_Scwrl_1JKN.pdb: