Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLSLKSLQCFVTLVKTKSFTRTAEELYLTQPTISKILQQLEEQLQVQLLVKPDHGRKRQIELTEIGERIYQHAGELLQAEQNIFLEIENYQQLKTGTLKLG-VPPLGSQLLTTALFDFHRQWPDIELAFMEVGSRGIEQALLNNELDVGVLLQPFDEQTFNSIELCNYPLMVLLRRDA--TWATRKKINLEELQHQSFLMFP----ENFSLNSIILDACKQHGFYPTIACRTSQWHLLADMVLQRMGIALLPQYYTDMLDPTLFAAVPLEKPNIQWHLVMAWKKNLPVSPAVQAWLSIVRQHF--QHIKP 2H98 Chain:A ((89-300)) ------------------------------------------------------------------------------------------SQ----TLRIGYVSSLLYGLLPEIIYLFRQQNPEIHIELIECGTKDQINALKQGKIDLGFGRLKITDPAIRRIMLHKEQLKLAIHKHHHLNQFAATGVHLSQIIDEPMLLYPVSQKPNFA--TFIQSLFTELGLVPSKLTEIREIQLALGLVAAGEGVCIVPASAMDIGVKNLL-YIPILDDDAYSPISLAV-RNMDHSNYIPKILACVQEVFATHHIRP

General information: TITO was launched using: RESULT: Template: 2H98.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1054 -34953 -33.16 -172.18 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : -33.16 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.507

(partial model without unconserved sides chains): PDB file : Tito_2H98.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2H98-query.scw PDB file : Tito_Scwrl_2H98.pdb: