Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHLHILGICGTFMGSLALLARDLGHKVTGSDSNVYPPMSTQLENAGIELMQGYDRSHLQPHPDLVIVGNAMKRGIDAVEYMLNEGLPYISGPQFLADHVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPLGFSESARLGGGKYFVVEADEYDSAFFDKRSKFVHYHPKTAILNNLEFDHADIF-DDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMGC-WTPVIRTSLEANEKAALSAELISI--DGSHFKVLENGNVIGEVKWSMTGQHSVANALATIAAAQHVGVSLEKACEALSNFGGVKRRMELLG----TVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTMRMGSHKDGLAHSARLADEVIWYQPEGL------DWDLQPVIEAATNH----AQVSRSLDEIIDRIVNEAGEGDAVVIMSNGGFGGLHQKLMSALKAKAA 1GQY Chain:B ((19-474)) QQIHFIGIGGAGMSGIAEILLNEGYQISGSDIADGV-VTQRLAQAGAKIYIGHAEEHI-EGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMR-FRHGIAVAGTHGKTTTTAMISMIYTQAKLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASF-------LHLQPMVSVVTNMEPDHMDTYEGDFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKVGRQVITYGFSEQA-DY---RIEDYEQTGFQGHYTVICPNNERINVLLNVPGKHNALNATAALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDDYGHHPTEVGVTIKAAREGWGDKRIVMIFQPHRYSRTRDLF-DDFVQVLSQVDALIMLDVYAAGEAPIVGADSKSLCRSIRNLGKVDPILVSDTSQLGDVLDQIIQDGDLILAQGAGSVSKISRGLAESWK----

General information: TITO was launched using: RESULT: Template: 1GQY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2494 -125420 -50.29 -286.35 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.75 3D Compatibility (PKB) : -50.29 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.554

(partial model without unconserved sides chains): PDB file : Tito_1GQY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GQY-query.scw PDB file : Tito_Scwrl_1GQY.pdb: