Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQDAKIALISEEESPVVDGLRKYLNDKE--TVVTL-DGTSQKEIDDA----LYFNRVNIILHLPADFTEQVEVGKMATIKIQSRPDAFS-KTVV-TQQVN--------TFLQTLILFQEE-DKTIDAAMEQTQMALSVTGEVELSAGYS-Q-RMKKLLTGTTFNFLSYGLFLSIFSGF--SVINLAFNRKEISKRNQSAPITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHT-SWDITVWYHILNTFLFLLPIISFSACITSLVKNSETSGGIKDIFITGSCFIGG-VFVPAEYLPEMVSKIAA-FTPTYWFVQNNN-------LISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN 5XJY Chain:A ((506-1118)) ---------------------------------------------------REAFNETNQAIRTISRFMECVNLNKLEPIATEVWLINKSMELLDERKFWAGIVFTGITPGSIELPHHVKYKIRMDIDNVERTNKIKDGYWDPGPRADPFEDMRYVWGGFAYLQDVVEQAIIRVLTGTEKKTGVYMQQMPYPCYVDDIFLRVMSRSMPLFMTLAWIYSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISSLIPLLVS--AGLLVVI-LKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQ----------------GFNLTTSVSMMLFDTFLYGVMTWYIEAV--------

General information: TITO was launched using: RESULT: Template: 5XJY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 837 -60810 -72.65 -194.90 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : -72.65 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.310

(partial model without unconserved sides chains): PDB file : Tito_5XJY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5XJY-query.scw PDB file : Tito_Scwrl_5XJY.pdb: