Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQGKVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTMFLPFLLTFVIMGTT----PLILGVTIV-HTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQVISLPAMILVAFLP-----MLSSLDKTVAKITD-YSFMGLFTKFFT-------KWEGFSWNETLIPNLTLLIWIVLLLTLITITIRKKKIS 5XJY Chain:A ((661-1117)) ------------------------------------------------------MPLFMTLAWI-YSVAVIIKGIVYEKEARLKETMRIMGLDNSILWFSWFISS-LIPLLVSAGLLVVILKLGNLLPYSDPSVVFVFLSVFAVVTILQCFLISTLFSRANLAAACGGIIYFTLYLPYVLCVAWQDYVGFTLKIFASLLSPVAFGFGCEYFALFEEQ----------GFNLTTSVSMMLFDTFLYGVMTWYIEA-

General information: TITO was launched using: RESULT: Template: 5XJY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 591 -98456 -166.59 -579.15 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -166.59 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.210

(partial model without unconserved sides chains): PDB file : Tito_5XJY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5XJY-query.scw PDB file : Tito_Scwrl_5XJY.pdb: