Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKILITGANTGIGFATAEQLVKQGQHVILACRNPQKAQEAQNKLRSLDQGQVDVASLDLNSLELTQKAAEEIADKYGSLDVLINNAGLFSKTKQLTVDGFEQKFGVNY----LGHFLLTQKLLPVLKQFPQAHIIHLASIAHWVGSIKPNKFRAEGFYNPLFYYGQSKLANLLFSNALAEQLADSSITNNALHPGGVASDIYRDLPKPVYAAMKVGLVPTSVPAKLITEMATGDTWQNRNGEYVSAHMPDWKSSHAKNQQLARDLYQQSMNLVEKFL 3AI3 Chain:A ((11-188)) ---VITGSSSGIGLAIAEGFAKEGAHIVLVARQVDRLHEAARSLKEKFGVRVLEVAVDVATPEGVDAVVESVRSSFGGADILVNNAG--TGSNETIMEAADEKWQFYWELLVMAAVRLARGLVPGMRARGGGAIIHNASIC----AVQPL------WYEPI--YNVTKAALMMFSKTLATEVIKDNIRVNCINPG----------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3AI3.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 870 -77924 -89.57 -447.84 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -89.57 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.515

(partial model without unconserved sides chains): PDB file : Tito_3AI3.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AI3-query.scw PDB file : Tito_Scwrl_3AI3.pdb: