Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKGSFMPASTSQYYTRTAQILHWVMAIIFITAWVIGFYSGNFLSYDV--DGSFKGDVITLHKNIATTIIFLVVIRLFWRYTHPAPQLPD----------------TMS--PTMKTLAHIGHLLLYVILVALPVTGCLFSWSAGHPAPVLYLFEIPRLVQDNPELLAIVKPLHIYISWFAGFLIVGHVLAALKHHFVDKDNVLNSMTKQPK 1KQG Chain:C ((2-188)) -------SKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLTQTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHKVADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYF-----AQ--YFP------MQVVRYSLLIHAAAGIILIHAILIHMYMAFWV-----KGSIKGMIEGKV

General information: TITO was launched using: RESULT: Template: 1KQG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 532 -91358 -171.72 -547.05 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain C : 0.63 3D Compatibility (PKB) : -171.72 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.286

(partial model without unconserved sides chains): PDB file : Tito_1KQG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KQG-query.scw PDB file : Tito_Scwrl_1KQG.pdb: