Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLDLFSPEPCSNLLPYDGVVQDYGCILTVEEAEQYFHYLYHHLAWRHD---EAKLYGKHFITPRKVAWYGDEHYRYKYSGVFRDSLPWDKALAQLKQQVEQILSEKFNSCLANLYEDGTQGMAWHSDSDVSLARTTTIASLSFGAMRKFSFRHIQTKEK-------VEMWLQPGQLIVMRGETQQYWQHRLNRSTKILQPRINLTFHQFKFS 3RZK Chain:A ((11-204)) -----------------EGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSR--PSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKI---

General information: TITO was launched using: RESULT: Template: 3RZK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 763 5145 6.74 28.42 target 2D structure prediction score : 0.48 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 6.74 2D Compatibility (Sec. Struct. Predict.) : 0.48 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.302

(partial model without unconserved sides chains): PDB file : Tito_3RZK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RZK-query.scw PDB file : Tito_Scwrl_3RZK.pdb: