Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTFVVTENCIKCKYQDCVEVCPVDCFYEGPNFLVINPDECIDCALCEPECPANAIFSEDELPEGQEVFIELNAELSQKWPNITQIGEQPADREEWNGKPDKLQYLEK 7FD1 Chain:A ((1-106)) -AFVVTDNCIKCKYTDCVEVCPVDCFYEGPNFLVIHPDECIDCALCEPECPAQAIFSEDEVPEDMQEFIQLNAELAEVWPNITEKKDPLPDAEDWDGVKGKLQHLER

General information: TITO was launched using: RESULT: Template: 7FD1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 514 -70423 -137.01 -664.37 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.90 3D Compatibility (PKB) : -137.01 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.90 QMean score : 0.509

(partial model without unconserved sides chains): PDB file : Tito_7FD1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-7FD1-query.scw PDB file : Tito_Scwrl_7FD1.pdb: