Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIIGYARTTINDVDLTTQVDQLSDFGCQ--EIFHETYEVEQNDSTAVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTR-EMGKIYFQLMENLANMECALIKERTLVGLDEARKKG-KIGGRPKIDAKTIKKIRRLYYEKKETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI 5CY2 Chain:A ((1-179)) MRIFGYARVSTSQQSLDIQIRALKDAGVKANRIFTDKAS---TDREGLDLLRM--KVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGDMGQMVVTILSAVAQAERRRILERTNEG------KGIKFGRRRTVDRNVVLTL----HQKGTGATEIAHQLSIARSTVYKIL------------

General information: TITO was launched using: RESULT: Template: 5CY2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 553 -21057 -38.08 -126.85 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -38.08 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.490

(partial model without unconserved sides chains): PDB file : Tito_5CY2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CY2-query.scw PDB file : Tito_Scwrl_5CY2.pdb: