Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNNQITLAYLDYDDLDALQVV--SVVSFYE-SFIDGADPLDMQGYLQTQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLGQRLL----DEANRYAKTNKNVIYV 1QSO Chain:A ((9-118)) ----ITVRFVTENDKEGWQRLWKSYQDFYEVSFPDDLDDFNFGRFLDPNIKM-WAAVAVESSSEKIIGMIN---FFNHMTTWDFKDKIYINDLYVDENSRVKGAGGKLIQFVYDEADK-----------

General information: TITO was launched using: RESULT: Template: 1QSO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 392 9369 23.90 90.96 target 2D structure prediction score : 0.30 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 23.90 2D Compatibility (Sec. Struct. Predict.) : 0.30 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.266

(partial model without unconserved sides chains): PDB file : Tito_1QSO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1QSO-query.scw PDB file : Tito_Scwrl_1QSO.pdb: