Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDLKWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECLERLQGKIKKYDRVLSRNKMECIK 1Q07 Chain:A ((1-110)) MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQL--------------------

General information: TITO was launched using: RESULT: Template: 1Q07.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 295 -36211 -122.75 -344.87 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -122.75 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.664

(partial model without unconserved sides chains): PDB file : Tito_1Q07.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Q07-query.scw PDB file : Tito_Scwrl_1Q07.pdb: