Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEH-GLKYDFVQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFILSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPIDPSRAIMSEKDHRHPTLKEFEAENPFVYGEI 1RTV Chain:A ((4-173)) MKATRLAIPDVILFEPRVFGDDRGFFFESYNQRAFEEACGHPVSFVQDNHSRSAR-GVLRGLHYQIRQA-QGKLVRATLGEVFDVAVDLRRGSPTFGQWVGERLSAENKRQMWIPAGFAHGFVVLSEYAEFLYKTTDFWAPEHERCIVWNDPELKIDWPLQDA-PLLSEKDRQ------------------

General information: TITO was launched using: RESULT: Template: 1RTV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 866 -30794 -35.56 -182.21 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -35.56 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.463

(partial model without unconserved sides chains): PDB file : Tito_1RTV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1RTV-query.scw PDB file : Tito_Scwrl_1RTV.pdb: