Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKQARKRILIGGGSEQPMRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSSTKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSILYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSRITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFGKITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL 1L2M Chain:A ((4-121)) ----------------------------------------------------------SGRFSIKAKNYFLTYPKCDLTKENALSQITN--------LQTPTNKLFIKICRELHENG----------------------EPHLHILIQF---EGKYNCTNQRFFDLVSPTRSAHFHPNIQGAKSSSDVKSYID-KDGDV-LEWGTFQIDGR----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1L2M.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 512 -32392 -63.26 -274.50 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -63.26 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.390

(partial model without unconserved sides chains): PDB file : Tito_1L2M.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1L2M-query.scw PDB file : Tito_Scwrl_1L2M.pdb: