Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPNPTDFQSSALATLRIEQQAIDVLATQIDDRFNRACEILLQCKGRVVITGMGKSGHIGRKMAATFASTGTPSFFMHPGEAGHGDLGMLVRGDVLIAISNSGKSDEIMMLMPLIKHLGVPLITISRDDKGPMPQNADIALTLGESDEACPLGLAPTSSTTATLVLGDALAVALLEARGFTADDFARSHPAGALGKRLLLHVKHLMHTGEELPKVSPETPMNQVLYEISNKRLGVTTIVDEQDHLLGIFTDGDLRRLIDKQQGFDVNLPVSEVMTKKPSTISQEARAVEALQQLNQKKISQFVVVDDQNKVIGVISMHDLIQAGVN--------------------------------------------------- 1PVM Chain:A ((7-184)) ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFMRVEKIMNS--NFKTVNWNTTVFDAVKIMNENHLYGLVVKDDNGNDVGLLSERSIIKRFIPRNKKPDEVPIRLVMRKPIPKVKSDYDVKDVAAYLSENGLERCAVVDDPGRVVGIVTLTDLSRYLSRASITDILLSHRTKDYQHLCPKCGVGVLEPVYNEKGEIKVFRCSNPACDYEE

General information: TITO was launched using: RESULT: Template: 1PVM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 587 -72828 -124.07 -573.44 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -124.07 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.511

(partial model without unconserved sides chains): PDB file : Tito_1PVM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1PVM-query.scw PDB file : Tito_Scwrl_1PVM.pdb: