Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDS-QFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGA-FKLPVEVVQYGAEQVFRHFERAGYKPSFREK--DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK 3IXQ Chain:C ((4-225)) -EDLKLKVAKEAVKLVKDGMVIGLGTGSTAALFIRELGNRIREEELTVFGIPTSFEAKMLAMQYEIPLVTLDE-YDVDIAFDGADEVEETTLFLIKGGGGCHTQEKIVDYNANEFVVLVDESKLVKKLGEKFPIPVEVIPSAYRVVIRALSEMGGEAVIRLGDRKRGPVITDNGNMIIDVFMN-IDDAIELEKEINNIPGVVENGIFTK-VDKVLVGTKKGVKTLK-----

General information: TITO was launched using: RESULT: Template: 3IXQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 1285 -45924 -35.74 -210.66 target 2D structure prediction score : 0.47 Monomeric hydrophicity matching model chain C : 0.82 3D Compatibility (PKB) : -35.74 2D Compatibility (Sec. Struct. Predict.) : 0.47 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_3IXQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3IXQ-query.scw PDB file : Tito_Scwrl_3IXQ.pdb: