Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQLTLVRHGEAAPPVNGNDIKRPLTARGHAQAEQTATFLKDI---VKPNIFVVSPLLRAQETLAHIQTYFKDVPVLLCDKIK---------------PDDDAKE-----AIEWLSQI------PYESIVVVCHMNVVGHIAELLTHET-----FNPFALAEARIYDQAVIANGLSTQKNSFIPTI 3EOZ Chain:B ((22-203)) KHIILVRH--------------RLTKEGCKQADITGKKLKDILNNKKVSVIYHSDMIRAKETANIISKYFPDANLINDPNLNEGTPYLPDPLPRHSKFDAQKIKEDNKRINKAYETYFYKPSDEDEYQLVICHGNVIRYFLCRALQIPLFAWLRF--YNCGITWLVLD----GSVVLREFGSV--

General information: TITO was launched using: RESULT: Template: 3EOZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 472 -20951 -44.39 -162.41 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.63 3D Compatibility (PKB) : -44.39 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_3EOZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EOZ-query.scw PDB file : Tito_Scwrl_3EOZ.pdb: