Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQLTLVRHGEAAPPVN---GNDIKRPLTARGHAQAEQTATFLKDIV-KPNIFVVSPLLRAQETLAHIQTYFKD--VPVLLCDKI-----------------------------------KPDDDAKE-----AIEWLSQI------PYESIVVVCHMNVVGHIAELLTHET-----FNPFALAEARIYDQAVIANGLSTQKNSFIPTI 1FZT Chain:A ((8-210)) NLLVLTRHGESEWNKLNLFTGWKDPALSETGIKEAKLGGERLKSRGYKFDIAFTSALQRAQKTCQIILEEVGEPNLETIKSEKLNERYYGDLQGLNKDDARKKWGAEQVQIWRRSYDIAPPNGESLKDTAERVLPYYKSTIVPHILKGEKVLIAAHGNSLRALIMDLEGLTGDQIVKRELATGVPIVYHLDKD--GKYVSKELID---

General information: TITO was launched using: RESULT: Template: 1FZT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 633 12518 19.77 85.74 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : 19.77 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.522

(partial model without unconserved sides chains): PDB file : Tito_1FZT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FZT-query.scw PDB file : Tito_Scwrl_1FZT.pdb: