Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTTVNAPEFVRHPKLIAWVEEIANLTKPAKIEWCDGSEEEYQRLIDLMIANGTMQKLNQEKHPGSYLANSDPSDVARVEDRTYICSQN---KEDA-----GATNNWEDPAVMREKLNGLFEGSMKGRTMYVVPFSMGPLGSHIAHIGIELTDSPYVAVSMRKMARMGKAVYDVLGTDGEFVPCVHTVGAPLAEG-QKDVAWPCNP-EKYIVHYPETREIWSFGSGYGGNALLGKKCLALRIASVMGREQGWLAEHMLILGVTNPQGEKHYIAAAFPSACGKTNFAMLIPPAGYEGWKIETVGDDIAWIKPGEDGRLYAINPEAGFFGVAPGTNTKTNPNCMATLHKDVIYTNVAVTDDGQVWWEGLSKEV-P-ANLTNWKGQPHVNG--EKAAHPNARFTVAAGQCPSIDADWENPAGVPISAFIFGGRRADTVPLVSEAFDWVDGVYKAATMGSETTAAAVGQQGIVRRDPFAMLPFAGYNMADYFDHWLNLGAKVSEKAEASGNKLPKIFNVNWFRRDAEGNFVWPGFGQNMRVLEWIIDRCEGRANAVETPIGFVPTYEDLNWEGTEFTKEQFDLITNQDKDQWVTEIESHTELF-NKLGERLPKALKERQAALLEAVKTGF 4GMU Chain:A ((14-612)) -KVIQGSLDSLPQEVRKFVEGNAQLCQPEYIHICDGSEEEYGRLLAHMQEEGVIRKLK--KYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKSGQSQLGRWMSEEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGTSVLEALG-DGEFIKCLHSVGCPLPLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKCFALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPTL--PGWKVECVGDDIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDEPLAPGVTITSWKNKEWRPQDEEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPAGVPLVYEALSWQHGVFVGAAMRSE---------G-IMHDPFAMRPFFGYNFGKYLAHWLSMAHRPA-------AKLPKIFHVNWFRKDKNGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYVPKEDALNLKGLG--DVNVEELFGISKEFWEKEVEEIDKYLEDQVNADLPYEIERELRALKQRISQM-

General information: TITO was launched using: RESULT: Template: 4GMU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3572 23808 6.67 40.77 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : 6.67 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.610

(partial model without unconserved sides chains): PDB file : Tito_4GMU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4GMU-query.scw PDB file : Tito_Scwrl_4GMU.pdb: