Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIILAIIQDKDSNRLSNELIDANIR-ATKLSSTGG--FL--------------KAGNSTFIVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLPVEGFHQF 4CO1 Chain:B ((1-101)) MKLVMAIIKPFKLDEVREALTSLGIQGLTVSEVKGFGRQKGQTEIYRGAEYSVSFLPKVKVEVAVSDDQYEQVVEAIQKAA-NTG-----------------------RIGDGKIFVLDIAQAVR-

General information: TITO was launched using: RESULT: Template: 4CO1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 284 -3413 -12.02 -40.63 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain B : 0.64 3D Compatibility (PKB) : -12.02 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.672

(partial model without unconserved sides chains): PDB file : Tito_4CO1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CO1-query.scw PDB file : Tito_Scwrl_4CO1.pdb: