Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLENDIKKVLVSHDEITEAAKKLGAQLTKDY-AGKNPILVGILKGSIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDIIDTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDYKENYRNLPYIGVLKEEVYSN 4RHY Chain:B ((17-200)) LYPGDIKSVLLTAEQIQARIAELGEQIGNDYR-GQDLLLITVLKGAVLFVTDLARAIPVPTQFEFMAVSSYG------GVVRILKDLDRDIHGRDVLIVEDVVDSGLTLSWLSRNLTSRNPRSLRVCTLLRKPDAVHANVEIAYVGFDIPNDFVVGYGLDYDERYRDLSYIGTLDPRVY--

General information: TITO was launched using: RESULT: Template: 4RHY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 852 -55013 -64.57 -321.71 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain B : 0.85 3D Compatibility (PKB) : -64.57 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.554

(partial model without unconserved sides chains): PDB file : Tito_4RHY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RHY-query.scw PDB file : Tito_Scwrl_4RHY.pdb: