Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKFNELNLSADLLAEIEKAGFVEASPIQEQTIP--LALEGKDVIGQAQTGTGKTAAFGLPTLEKIRT----EEATIQALVIAPTRELAVQSQEEL-----FRFGRSKGVKVRSVYGGSSIEKQIKAL-KSGAHIVVGTPGRLLDLIKRKALKL-QDIETLILDEADEMLNMGFLEDIEAII-------SRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELT----TELVDQYYIRVKEQEKF-DTMTRLMDVAQPEL--------AIVFGRTKRRVDELTRGLKIRGFRAE----GIHGDLDQNKRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAGKSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADETIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGNGFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNTLSEKQTGFVIRNKGDK 4TYW Chain:A ((27-407)) -------LDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKKYACV-SLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQ---SVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCSILK-NEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELED------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4TYW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1759 91718 52.14 266.62 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 52.14 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.477

(partial model without unconserved sides chains): PDB file : Tito_4TYW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4TYW-query.scw PDB file : Tito_Scwrl_4TYW.pdb: