Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKAITDATFEQET--KDGLVLVDFWATWCGPCRMQGPILDKLSEELSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTVEQIKAIIAELS 2EIQ Chain:A ((7-103)) ----LTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEY-QGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAACKVGALSKGQLKEFL----

General information: TITO was launched using: RESULT: Template: 2EIQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 396 2927 7.39 30.81 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : 7.39 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.663

(partial model without unconserved sides chains): PDB file : Tito_2EIQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2EIQ-query.scw PDB file : Tito_Scwrl_2EIQ.pdb: