Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSTPEQLPALSAAGSPSSGGASSHHSPHEASLSFPASVIPGDASAESPRAWSMPRSSTASEESAATSQLQQKPDAPESRLGGRKVVYFVDHSVTSIAYAEGHLMRPSRVRALHALVHSLGLDNAECMTVCHARPATAEEMGAFHRSAYLECLRQAPVICGNPLDEMSLAFQKEFDVPFASQNG---DCPLFPEVWALVSSQAGASLACAEALVRGDATVAMNWAGGMHHAAAAHASGFCFVNDIVLCIRRLLRHYQRVLYVDLDVHHGDGVEGAFYGNHRVMTLSLHQFGNGFFPGTGDYPTRETADS--FAINVPLPTRTGDAAYLLSFRTALSSVVQCFDPEAMVVQCGADTIAGDLIGRLCVTTLAHTQCVADVLSLERPTVLLGGGGYHVFHTARCWAIHTATALGRT-AAQLP---LYIPRTDPYYMDYRRECTPKRPTLHVFLDPDVDDPLPLGDSLAFWRQLCRSIQWQMRAARLVRQGFFRTLQLCRQRRAALLRQFATQEAGRESGIGVSGPKRPRSANATDRDAKEGVEDRVVSA 4QA5 Chain:A ((14-360)) ------------------------------------------------------------------------------------LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQ--MRIVKPKVASMEEMATFHTDAYLQHLQK-------------VSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDTFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGFNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH---------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4QA5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2090 -111596 -53.39 -330.16 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : -53.39 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.486

(partial model without unconserved sides chains): PDB file : Tito_4QA5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QA5-query.scw PDB file : Tito_Scwrl_4QA5.pdb: