Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MATAVNCNICFIGGGNMAQALIGGLISRGLPPTRITVSDPVEQIR-QLLQE-KEV-HVTQDNTAAIQNADVVVLAVKPQVLANVLRPLKGLL-SD-KLVISIIAGAEIKTISNLID-SERIVRVMPNTPALVQTGAHGIYATDVVGASDRELTSQILAATGLTIWVNSEAQIDAVTAVSGSGPAYFFYLMESMIRAGKNLGLDEKVATALTLQTALGAAQMAITSSNTPSELRKNVTSPNGTTQAALEVFDRAQISQNIQSALAVAQKRSQELAQELSDSAK 3TRI Chain:A ((2-273)) ----NTSNITFIGGGNMARNIVVGLIANGYDPNRICVTNRS-LDKLDFFKEKCGVHTT-QDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISLAVGVTTPLIEKWLGKASRIVRAMPNTPSSVRAGATGLFANETVDKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPAYIFLIMEALQEAAEQLGLTKETAELLTEQTVLGAARMALETEQSVVQLRQFVTSPGGTTEQAIKVLESGNLRELFIKALTAAVNRAKELSKTVD----

General information: TITO was launched using: RESULT: Template: 3TRI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1188 -41100 -34.60 -154.51 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.82 3D Compatibility (PKB) : -34.60 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.530

(partial model without unconserved sides chains): PDB file : Tito_3TRI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TRI-query.scw PDB file : Tito_Scwrl_3TRI.pdb: