Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLINTEVKPFQATAYHNGQFIEVNETNLKGKWSVVFFYPADFTFVCPTELEDLADNYAEFQKLGVEIYGVSTDTHFTHKAWHDTSDAIKKIQYPLIGDPTWTLSKNFDVLIESEGLADRGTFVIDPEGKIQIVEINAGGIGRDASELLRKVKAAQYVHSHPGEVCPAKWKEGEATLAPSIDLVGKI 4MAB Chain:E ((1-186)) -SLINTKIKPFKNQAFKNGEFIEVTEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYSVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAAHPGE----KWKEGEATLAPSLDLVGKI

General information: TITO was launched using: RESULT: Template: 4MAB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain E - contact count / total energy / energy per contact / energy per residue : 831 -79622 -95.81 -437.48 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain E : 0.93 3D Compatibility (PKB) : -95.81 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.93 QMean score : 0.633

(partial model without unconserved sides chains): PDB file : Tito_4MAB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4MAB-query.scw PDB file : Tito_Scwrl_4MAB.pdb: