Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNDKTARQKILDAAATLFYNDGITATGINTVTAKADVAKMSLYNNFSSKGELVDAYIAARHQEWLDLYQKRLEKTKTAKEAILAVFDAYQDHAEFAYEKGFRGCGLLNAAAEFPA-NSSGRNAVRQHKEQVEAIVAEHLNRLL-----KDSQRVSYIASQLSFLLEGSMARAGLEGSSRQLQLARQMAEDILDRECQHD 2HYJ Chain:A ((9-198)) -EAQATRGRILGRAAEIASEEGLDGITIGRLAEELEMSKSGVHKHFGTKETLQISTLDKAFVDFWHRVVEPALAEPPGLRRLRAVCANSVGYLEE--PLLPGGCLLTAALSEYDGRPGRVRDAVAEVWSRWREQLRADLTAAVDKGELPAGFDVEQALFEIVAAGLALNAAMQLQHDRTAADRARRAIERALA------

General information: TITO was launched using: RESULT: Template: 2HYJ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 745 -39368 -52.84 -213.95 target 2D structure prediction score : 0.75 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -52.84 2D Compatibility (Sec. Struct. Predict.) : 0.75 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.657

(partial model without unconserved sides chains): PDB file : Tito_2HYJ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HYJ-query.scw PDB file : Tito_Scwrl_2HYJ.pdb: