Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKIVAIWAQDEEGLIGKENRLPWHLPAELQHFKETTLNHAILMGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGGKQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTIQYRKRKEV 3TQB Chain:A ((3-160)) ----ITLIAAMDKNRLIGRNNELPWHLPADLAHFKSITLGKPIVMGRRTFDSIGKP-LPHRRNIVITQQKNLIIEGCDIFYSLDDALSALT-KEPEVIIIGGARIFKEALPKADKMILTIINHSFEGDVYFPEWNDKE-WKITSQIKH---------FQFLELRR---

General information: TITO was launched using: RESULT: Template: 3TQB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 696 -120750 -173.49 -810.40 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -173.49 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.561

(partial model without unconserved sides chains): PDB file : Tito_3TQB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3TQB-query.scw PDB file : Tito_Scwrl_3TQB.pdb: