Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAELLTLARPYAKAAFAYASEQGATDNWSNALQVLSAA------VQDEAFSAYLNRPEHTPAEQVKLFAKVLGEDQSQAVSNFLTLLADNDRLVLLPEIAAEYEQLKSQNNNNVDVVIESAFPLTAEQEQLLKSALEKRFNSTVTVSVEVKPELIAGVVIRAGDQVIDDSALNKLEKMRTRLLA 5DN6 Chain:H ((13-115)) ------IAGRYAQALFDLVRDSGGIDALSSQIDDLASAYDASQDLRDLTLSPLYDRQQQEAA--VGALSERMG--LSAELANTLRLLARNRRLFTLPQFVAKLRNLIADAKGE-----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5DN6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain H - contact count / total energy / energy per contact / energy per residue : 347 -7911 -22.80 -81.56 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain H : 0.68 3D Compatibility (PKB) : -22.80 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.568

(partial model without unconserved sides chains): PDB file : Tito_5DN6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5DN6-query.scw PDB file : Tito_Scwrl_5DN6.pdb: