Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVAGLTNGELIAPMTYEEMVTSDFFEAWFQKFLLPTLT-----TPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNP-IEKTWAYIKKNLKKVLPSCNTFYEALFSCSCFN 5M0Q Chain:A ((97-178)) -----------------------------QEFRVQTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLEKLIPMFNAFESAL-------

General information: TITO was launched using: RESULT: Template: 5M0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 165 6662 40.38 87.66 target 2D structure prediction score : 0.66 Monomeric hydrophicity matching model chain A : 0.59 3D Compatibility (PKB) : 40.38 2D Compatibility (Sec. Struct. Predict.) : 0.66 1D Compatibility (Hydrophobicity) : 0.59 QMean score : 0.404

(partial model without unconserved sides chains): PDB file : Tito_5M0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5M0Q-query.scw PDB file : Tito_Scwrl_5M0Q.pdb: